Human
aging may have been influenced by millions of years of dinosaur dominance, according
to a new theory from a leading aging expert
The
“longevity bottleneck” hypothesis has been proposed by Professor Joao Pedro de
Magalhaes of the University of Birminghan in a new study published in
BioEssays. The hypothesis relates the role that dinosaurs played for more than
100 million years to aging process of mammals.
While
some reptiles and amphibians do not show significant sings of aging, all
mammals, including humans, show a marked aging process.
Professor
de Magalhaes’s hypothesis suggests that during the Mesozoic Era, mammals faced
persistent pressure for rapid reproduction during the reign of the dinosaurs,
which for more than 100 million years led to the loss or inactivation of genes
associated with long life, such as processes with tissue regeneration and DNA
repair.
Joao
Pedro de Magalhaes, Professor of Molecular Biogerontology at the Institute of
Inflammation and Aging at the University of Birminghan, explain: “The ‘longevity
bottleneck hypothesis’ may shed light on the evolutionary forces that have
shaped the aging of people. Mammals for millions of years. While humans are
among the longest-lived animals, there are many reptiles and other animals that
have a much slower aging process and show minimal sings of senescence
throughout their lives”.